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Tocris Bioscience™ BAY 1816032
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Product Code. 18769776
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Quantity:
10 mg
Unit Size:
10mg
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Product Code. 18769776

Brand: Tocris Bioscience™ 7549/10

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This item is not returnable. View return policy

Description

Potent and selective BUB1 kinase inhibitor

BAY 1816032 is a potent and selective inhibitor of BUB1 kinase, a mitotic checkpoint serine/threonine kinase (IC50 = 6.1 nM). BAY 1816032 shows 17-fold selectivity over a panel of 403 other human kinases. In vivo, BAY 1816032 decreases tumor size in tumor xenograft models. BAY 181603 is orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 2-[3,5-Difluoro-4-[[3-[5-methoxy-4-[(3-methoxy-4-pyridinyl)amino]-2-pyrimidinyl]-1 H-indazol-1-yl]methyl]phenoxy]ethanol
CAS 1891087-61-8
Quantity 10 mg
Target Checkpoint Control Kinase Inhibitors
Molecular Formula C27H24F2N6O4
Purity 0.98
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