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Bax Antibody (2D2), Novus Biologicals™

Product Code. 18419901 Shop All Bio Techne Products
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0.1 mg
20 ug
Unit Size:
0.10mg
20µg
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Product Code. Quantity unitSize
18419901 20 ug 20µg
18189104 0.1 mg 0.10mg
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Product Code. 18419901 Supplier Novus Biologicals Supplier No. NBP22946820ug

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Description

Mouse Monoclonal Antibody has been used in 1 publication

Bax Monoclonal specifically detects Bax in Human, Monkey, Mouse (Negative), Rat (Negative) samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Bax
Applications Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 2D2
Concentration 0.2 mg/ml
Conjugate Unconjugated
Dilution Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunohistochemistry 0.5-1ug/ml, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
Gene Accession No. Q07812
Gene Alias apoptosis regulator BAX, BCL2-associated X protein, Bcl2-L-4, BCL2L4bcl2-L-4, Bcl-2-like protein 4
Gene Symbols BAX
Host Species Mouse
Immunogen A synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein. (Uniprot: Q07812)
Molecular Weight of Antigen 21 kDa
Purification Method Protein A or G purified
Quantity 20 ug
Regulatory Status RUO
Research Discipline Apoptosis, Cancer, Core ESC Like Genes, Stem Cell Markers, Tumor Suppressors
Primary or Secondary Primary
Gene ID (Entrez) 581
Test Specificity Recognizes a protein of 21kDa, identified as the Bax protein. This monoclonal antibody is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
Target Species Human, Monkey, Mouse (Negative), Rat (Negative)
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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