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Invitrogen™ BATF Polyclonal Antibody

Description
Immunogen sequence: DSSDSSFSRS PPPGKQDSSD DVRRVQRREK Highest antigen sequence indentity to the following orthologs: Mouse - 97%, Rat - 97%.
BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events and blocks cellular transformation by Ras and Fos. BATF also is required for the differentiation of IL-17-producing T helper (TH17) cells, a CD4+ subset of T cells that coordinates the inflammatory response in host defense. In both T cells and B cells, BATF is required for the appropriate regulation of the class-switch recombination.
Specifications
Specifications
| Antigen | BATF |
| Applications | Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.05 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | Batf |
| Gene Accession No. | Q16520 |
| Gene Alias | activating transcription factor B; basic leucine zipper ATF-like transcription factor; basic leucine zipper transcription factor, ATF-like; basic leucine zipper transcription factor-like; basic leucine zipper transcriptional factor ATF-like; BATF; B-ATF; BATF1; B-cell activating transcription factor; B-cell-activating transcription factor; SFA2; SFA-2; SF-HT-activated gene 2 protein; si:ch211-153j24.4 |
| Gene Symbols | Batf |
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