Invitrogen™ BAP31 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA520199

Product Code. 12858232

Description

A suggested positive control is rat lung tissue lysate. PA5-20199 can be used with blocking peptide PEP-0327.

BAP31 (B-Cell Receptor Associated Protein, 31-kDa) is a multiple membrane spanning protein of the endoplasmic reticulum. It has been shown to form both homo- and hetero-oligomers with the closely related BAP29, and is a potential apoptotic regulator as a predicted BCL-2/BCL-XL-associated protein. In the C-terminal domain of BAP31, there are two identical recognition sites for initiator Caspases 1 and 8 of the programmed death cascade. It is hypothesized that BAP31 plays a role in the transport of selected proteins to the Golgi apparatus. BAP31 has also been shown to control expression of CFTR (cystic fibrosis transmembrane conductance regulator). It is believed that interference with the expression or function of BAP31 in epithelial cells may be a way to circumvent the chloride channel defect in cystic fibrosis.

Specifications

• Antigen: BAP31
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BCAP31
• Gene Alias: 6C6 antigen; 6C6-AG; 6C6-AG tumor-associated antigen; accessory protein BAP31; B cell receptor associated protein 31; BAP31; Bcap31; B-cell receptor-associated protein 31; BCR-associated protein 31; BCR-associated protein Bap31; CDM; CDM protein; DDCH; DXS1357E; hypothetical protein LOC533949; OTTHUMP00000025978; p28; p28 Bap31; Protein CDM
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10134, 27061, 293852
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P51572, Q61335
• Gene Symbols: BCAP31
• Immunogen: A 17 amino acid peptide from near the center of human BAP31.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG