Invitrogen™ BAP3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA553347

Product Code. 15721291

Description

Immunogen sequence: ATLFYTELLR KKVDTQPGAA GEAVSEALCV VLNNVELVRK AAGQALKGLA WPEGATGPEG VLPRPLLSCT QALDDDLQRE AHTVTAHLTS KMVGDIRKYV QHISLSPDSI QNDEAVAPLM KYLDEKLALL NASLVKGNLS Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 89%.

BAP3 was initially identified through interaction in a yeast two-hybrid system with the brain-specific angiogenesis inhibitor 1, a p53-target gene that encodes a seven-span transmembrane protein member of the secretin receptor family. BAP3 is predominantly expressed in the brain and possess high homology with Munc13 and synaptotagmin, suggesting that BAP3 may play a role in regulating neurotransmitter release. Recent experiments have shown that BAP3 is induced in certain tumors such as desmoplastic small round cell tumor. Ectopic expression of BAP3 in tumor cells dramatically enhances growth in low serum conditions and colony formation in soft agar, suggesting that the regulated exocytotic pathway may play a role in cancer cell proliferation.

Specifications

• Antigen: BAP3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BAIAP3
• Gene Alias: AL031709.1; BAI1 associated protein 3; BAI1-associated protein 3; BAIAP3; BAI-associated protein 3; BAP3; Brain-specific angiogenesis inhibitor I-associated protein 3; Gm937; KIAA0734
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8938
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O94812
• Gene Symbols: BAIAP3
• Immunogen: Recombinant protein corresponding to Human BAP3. Recombinant protein control fragment (Product #RP-90656).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG