BAP29 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA520195

Product Code. 12828232

Description

This antibody is specific for isoform A of Bap29. A suggested positive control is human heart tissue lysate. PA5-20195 can be used with blocking peptide PEP-0325.

Bap29 and the related protein Bap31 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Both Bap29 and Bap31 interact with membrane-bound immunoglobulins (mIgs), such as IgM and IgD, which with Ig-alpha/Ig-beta heterodimers form B cell antigen receptors. Binding of the Bap29/Bap31 heterodimer correlates with the ER retention of non-Ig-alpha/Ig-beta bound mIg complexes, suggesting that Bap29 and Bap31 may act as chaperones transmembrane regions of various proteins. Bap29 possesses multiple isoforms.

Specifications

• Antigen: BAP29
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Bcap29
• Gene Alias: AW208404; B cell receptor associated protein 29; BAP29; Bcap29; B-cell receptor-associated protein 29; B-cell receptor-associated protein BAP29; BCR-associated protein 29
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12033, 298943, 55973
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q61334, Q9UHQ4
• Gene Symbols: Bcap29
• Immunogen: A 17 amino acid synthetic peptide from near the center of human Bap29
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG