Invitrogen™ BANF1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA558710

Product Code. 15796581

Description

Immunogen sequence: MTTSQKHRDF VAEPMGEKPV GSLAGIGEVL GKKLEERGFD KAYVVLGQFL VLKKDEDLFR EWLKDTCGAN AKQSRDCFGC Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

Barrier-to-autointegration factor 1 (BANF1) is a conserved chromatin protein that non-specifically binds double-stranded DNA. BANF1 also interacts with a family of nuclear proteins that include LAP2, emerin, and MAN1. It is also a host cell component of retroviral pre-integration complexes (PICs), including that of HIV. BANF1 will bind to p55 Gag (the structural precursor of HIV-1 virions) as well as its cleaved product matrix. In addition to being a host cell component of the PIC, it is thought that BANF1 is also present at low levels in incoming virions, and thus might contribute to the assembly or activity of HIV-1 PICs through direct binding to matrix as well as DNA.

Specifications

• Antigen: BANF1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BANF1
• Gene Alias: Baf; Banf1; barrier to autointegration factor 1; barrier-to-autointegration factor; Barrier-to-autointegration factor, N-terminally processed; BCRG1; Bcrp1; breakpoint cluster region protein 1; Breakpoint cluster region protein, uterine leiomyoma, 1; Breakpoint cluster region protein, uterine leiomyoma, 1; barrier to autointegration factor; D14S1460; L2bp1; L2bp1/Baf; Lap2 binding protein 1; LAP2-binding protein 1; NGPS
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8815
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O75531
• Gene Symbols: BANF1
• Immunogen: Recombinant protein corresponding to Human BANF1. Recombinant protein control fragment (Product #RP-102866).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG