Invitrogen™ BAMBI Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA5148590

Product Code. 30536050

Description

Reconstitute at 0.2 mg/mL in sterile PBS.

BAMBI (BMP and activin membrane-bound inhibitor homolog, NMA) is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development. BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.

Specifications

• Antigen: BAMBI
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BAMBI
• Gene Alias: 2610003H06Rik; BAMBI; BMP and activin membrane bound inhibitor; BMP and activin membrane-bound inhibitor; BMP and activin membrane-bound inhibitor homolog; BMP and activin membrane-bound inhibitor, homolog; kinase-deficient TGFbeta superfamily receptor subunit; NMA; Non-metastatic gene A protein; putative transmembrane protein NMA
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 68010
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with trehalose and no preservative
• Gene Accession No.: Q9D0L6
• Gene Symbols: BAMBI
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse BAMBI/NMA, Ile28-Thr143.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG