BAK1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA5109442

Product Code. 17157373

Description

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Specifications

• Antigen: BAK1
• Classification: Polyclonal
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O08734, Q16611
• Gene Symbols: BAK1
• Immunogen: A synthetic peptide of human BAK1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Gene: BAK1
• Gene Alias: Apoptosis regulator BAK; BAK; BAK1; BAK-LIKE; Bcl-2 homologous antagonist/killer; BCL2L7; Bcl2-L-7; BCL2-like 7protein; Bcl-2-like protein 7; CDN1; MGC117255; MGC3887; N-Bak; N-BAK1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116502, 12018, 578
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid