BACE-1 Antibody, Novus Biologicals™

Rabbit Polyclonal Antibody

Brand:  Novus Biologicals NBP1-77307-0.025mg

Product Code. 18732954

Description

BACE-1 Polyclonal specifically detects BACE-1 in Human, Mouse samples. It is validated for Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: BACE-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Formulation: PBS with 0.02% Sodium Azide
• Gene Alias: APP beta-secretase, ASP2, Aspartyl protease 2, BACEAsp 2, beta-secretase 1, beta-secretase 1 precursor variant 1, beta-site amyloid beta A4 precursor protein-cleaving enzyme, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, beta-site APP-cleaving enzyme, beta-site APP-cleaving enzyme 1, EC 3.4.23, EC 3.4.23.46, FLJ90568, HSPC104, KIAA1149, Memapsin-2, Membrane-associated aspartic protease 2, transmembrane aspartic proteinase Asp2
• Host Species: Rabbit
• Molecular Weight of Antigen: 55 kDa
• Quantity: 0.025 mg
• Research Discipline: Neurodegeneration, Neuroscience
• Gene ID (Entrez): 23621
• Target Species: Human, Mouse
• Isotype: IgG

• Applications: Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Dilution: Western Blot 1 μg/mL, ELISA 1:100-1:2000, Immunohistochemistry 2.5 μg/mL, Immunocytochemistry/Immunofluorescence 10-20 μg/mL, Immunohistochemistry-Paraffin 2.5 μg/mL
• Gene Accession No.: AF190725
• Gene Symbols: BACE1
• Immunogen: Antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human BACE. The immunogen is located within the last 50 amino acids of BACE. Amino Acid Squence: CLRQQHDDFADDISLL
• Purification Method: Ion exchange chromatography
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Human BACE-1 has 6 isoforms, including isoform A (501aa, 55.8kD), isoform B (476aa, 52.9kD), isoform C (457aa, 51.1kD), isoform D (432aa, 48.2kD), isoform 5 (401aa, 45kD) and isoform 6 (376aa, 42.2kD). This antibody detects all human isoforms. Mouse BACE-1 has only 1 isoform (501aa, 55.7kD). Rat BACE-1 has only one isoform identified so far (501aa, 55.8kD).
• Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For Research Use Only