Invitrogen™ B1 Bradykinin Receptor Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA533361

Product Code. 15324511

Description

This antibody is not recommended for use in ELISA applications. Percent identity with other species by BLAST analysis: Human (100%) Gorilla, Gibbon, Monkey (94%) Horse (81%).

Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.

Specifications

• Antigen: B1 Bradykinin Receptor
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Bdkrb1
• Gene Alias: B1 bradykinin receptor; B1BKR; B1R; Bdkrb; BDKRB1; BDKRB2; Bk b1 receptor; BK-1 receptor; BKB1R; BKR; BKR1; BKRB1; BRADYB1; bradykinin B1 receptor; bradykinin receptor 1; bradykinin receptor B1; bradykinin receptor B2; bradykinin receptor, beta 1; KB1; kinin B1; kinin B1 receptor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 623
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P46663
• Gene Symbols: Bdkrb1
• Immunogen: Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human BDKRB1.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG