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B-Myb Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16818734 Shop All Proteintech Products
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16818734 20 μL 20µL
16808734 150 μL 150µL
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Product Code. 16818734 Supplier Proteintech Supplier No. 188961AP20UL

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Rabbit Polyclonal Antibody

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.

Specifications

Antigen B-Myb
Applications Immunoprecipitation, Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MYBL2
Gene Accession No. P10244, P48972
Gene Alias B MYB, BMYB, B-Myb, Myb like protein 2, Myb related protein B, MYBL2
Gene Symbols Mybl2
Host Species Rabbit
Immunogen B-Myb Fusion Protein Ag13525
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17865, 296344, 4605
Target Species Mouse, Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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