Invitrogen™ AZGP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA552951

Product Code. 15740901

Description

Immunogen sequence: QDGRYSLTYI YTGLSKHVED VPAFQALGSL NDLQFFRYNS KDRKSQPMGL WRQVEGMEDW KQDSQLQKAR EDIFMETLKD IVEYYNDSNG SHVLQGRFGC EIENNRSSGA FWKYYYDGKD YI Highest antigen sequence identity to the following orthologs: Mouse - 61%, Rat - 59%.

Alpha-2-glycoprotein 1, zinc-binding (AZGP1) is a gene encoding a protein that belongs to the immunoglobulin superfamily. This protein is abundant in various body fluids, such as blood plasma and milk, and is involved in lipid mobilization. AZGP1 is expressed in numerous tissues, including the liver, prostate, and adipose tissue, where it plays a significant role in the regulation of lipid metabolism and adipocyte function. It acts as an adipokine, influencing the breakdown and mobilization of fats, thereby contributing to energy homeostasis. In cancer research, AZGP1 has been highlighted for its potential as a prognostic biomarker, particularly in prostate and breast cancer, where lower expression levels are often associated with poor prognosis. Recent studies have also linked AZGP1 to cachexia, an extreme form of weight loss and muscle wasting, by promoting lipid mobilization in adipose tissue and influencing systemic catabolic states. Due to its multifaceted roles in lipid metabolism and disease processes, AZGP1 is considered a promising target for therapeutic interventions in metabolic and cancer-related disorders.

Specifications

• Antigen: AZGP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AZGP1
• Gene Alias: alpha-2 - glycoprotein 1 zinc; alpha-2 - glycoprotein 1, zinc; alpha-2-glycoprotein 1, zinc; alpha-2-glycoprotein 1, zinc-binding; Alpha-2-glycoprotein, zinc; Azgp1; major histocompatibility complex class I-like protein; testicular tissue protein Li 227; ZA2G; ZA2GA; Zag; Zinc a 2 glycoprotein; Zinc a2glycoprotein; Zinc alpha2glycoprotein; zinc alpha-2-glycoprotein 1; Zinc α 2 glycoprotein; Zinc α2glycoprotein; zinc-alpha-2-glycoprotein; Zn - alpha2 - glycoprotein; Zn a 2 glycoprotein; Zn a 2 GP; Zn alpha 2 glycoprotein; Zn alpha 2 GP; Zn α 2 glycoprotein; Zn α 2 GP; Zna2gp; zn-alpha-2-glycoprotein; Zn-alpha2-glycoprotein; zn-alpha-2-GP; ZNGP1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 563
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P25311
• Gene Symbols: AZGP1
• Immunogen: Recombinant protein corresponding to Human AZGP1. Recombinant protein control fragment (Product #RP-100376).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG