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Eurofins DiscoverX Axl Protein, Active
Description
AXL is a member of AXL protein-tyrosine kinase family and expressed human myeloid leukemia cells. Gas6, the protein product of the growth arrest-specific gene 6 (gas6), a member of the vitamin K-dependent protein family, was identified as a ligand for the Axl/Sky family of receptor tyrosine kinases. Gas6/Axl signaling has been related to the cell growth and protection from apoptosis in normal and cancer cells.
GenBank NM_021913. The recombinant protein also contains the conflict Q764R with respect toGenBank NM_021913. This substitution is reported in GenBank BC032229. The residue coordinates in the native sequence are given.
Specifications
Specifications
| Formulation | mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 150 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
| Molecular Weight (g/mol) | 48 kDa |
| Quantity | 10 μg |
| Species | Human |
| Recombinant | Recombinant |
| Protein Tag | N-terminal 5His |
| Expression System | Recombinant enzyme expressed in Sf21 insect cells |
| Protein Form | Truncated |
| Purity or Quality Grade | ≥41% |
| Protein | Axl, active |
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