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Eurofins DiscoverX Aurora C Protein, Active

Product Code. 17360774
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Quantity:
10 μg
250 μg
Unit Size:
10µg
250µg
This item is not returnable. View return policy

Product Code. 17360774

Brand: Eurofins DiscoverX 14911

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This item is not returnable. View return policy

Description

Active, N-terminal 6His-tagged, recombinant, human Aurora C amino acids 35-end and N-terminal GST-tagged, recombinant, human INCENP, amino acids 821-end, for use in Kinase Assays.

Aurora C Protein is a member of the Aurora subfamily of serine/threonine protein kinases. It is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

GenBank AB017332.1 / GenBank NM_020238.2

Specifications

Formulation mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Molecular Weight (g/mol) 36 kDa (Aurora C) and 38 kDa (INCENP)
Quantity 10 μg
Species Human
Recombinant Recombinant
Protein Tag N-terminal 6His / N-terminal GST
Expression System Recombinant enzyme expressed in Sf21 insect cells
Protein Form Truncated
Purity or Quality Grade Combined ≥74% ratio 1:1.4 AurC:INCENP
Protein Aurora C, active
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