Atropine sulfate monohydrate, 97+%

Product Code. 10328270

Brand: Thermo Scientific Acros 226680100

Description

Atropine sulfate monohydrate, CAS # 5908-99-6, is a muscarinic receptor antagonist. | CAS: 5908-99-6 | H₂SO₄·H₂O | 694.85 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Atropine is a competitive and reversible antagonist of muscarinic acetylcholine receptors on both central and peripheral neurons
• Atropine was originally isolated from the belladonna plant Atropa belladonna but is also found in other Solanaceae plants
• Atropine is a drug that can be used to slow heart rate, decrease salivary secretions, and treat poisoning caused by cholinergic or muscarinic agents

Applications

• It is used to block activation of muscarinic receptors in laboratory mice
• It can be used in a laboratory setting to decrease oral and airway secretions in research animals
• Atropine has been used to study heart rate and blood pressure variability in swine

Specifications

Chemical Identifiers

• CAS: 5908-99-6
• Molecular Formula: H₂SO₄·H₂O
• Molecular Weight (g/mol): 694.85
• MDL Number: MFCD00074815
• InChI Key: PVGPXGKNDGTPTD-IJTOKZDFSA-N
• Synonym: atropine sulfate hydrate, atropine sulfate monohydrate, 1r,3s,5s-8-methyl-8-azabicyclo 3.2.1 octan-3-yl 3-hydroxy-2-phenylpropanoate; methane; sulfuric acid
• PubChem CID: 23624044
• IUPAC Name: [(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate;sulfuric acid;hydrate
• SMILES: CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.O.OS(=O)(=O)O

• Acidity: Passes Test
• Melting Point: >187.0°C
• Color: White
• Ignition Residue: 0.2% max.
• Infrared Spectrum: Authentic
• Assay Percent Range: 97+%
• Packaging: Glass bottle
• Quantity: 10 g
• Beilstein: 21, 27
• Merck Index: 15, 866
• Specific Rotation: − 0.60
• Solubility Information: Solubility in water: soluble. Other solubilities: soluble in boiling alcohol and glycerol, slightly soluble in chloroform, practically insoluble in ether
• Formula Weight: 694.85
• Percent Purity: 97+%
• Physical Form: Powder
• Chemical Name or Material: Atropine sulfate monohydrate

Safety and Handling

Product Identifier

• Atropine sulfate monohydrate

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 2

Hazard Statement

• H300-Fatal if swallowed.
• H330-Fatal if inhaled.

Precautionary Statement

• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P264-Wash thoroughly after handling.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P310-Immediately call a POISON CENTER/doctor/.
• P403+P233-Store in a well-ventilated place. Keep container tightly closed.
• P405-Store locked up.

SDS

RUO – Research Use Only