Atpenin A5, MP Biomedicals™

Product Code.	Quantity	unitSize
15917305	1 mg	1mg

Product Code. 15917305 Supplier MP Biomedicals Supplier No. 0218335701

Description

Mitochondrial Complex II (succinate dehydrogenase or succinate:ubiquinone oxidoreductase) couples the oxidation of succinate to fumarate with the reduction of quinone to quinol. It is a member of the Krebs cycle.

• Highly selective compound, ubiquinone-binding site mitochondrial complex II inhibitor, stimulates mitochondrial channels
• Shows anti-ischemic and cardioprotective effects in vivo
• Used in the Krebs cycle to fumarate with the reduction of quinone to quinol

Specifications

• CAS: 119509-24-9
• Synonym: FO 125A5, atpenin A5, Antibiotic FO 125A5, Atpenin A5 (Synthetic), (2 S,4 S,5 R)-5,6-Dichloro-1-(2,4-dihydroxy-5,6-dimethoxypyridin-3-yl)-2,4-dimethyl-1-hexanone, (2 S,4 S,5 R)-1-(2,4-Dihydroxy-5,6-dimethoxy-3-pyridinyl)-2,4-dimethyl-5,6-dichloro-1-hexanone, 3-[(2 S,4 S,5 R)-5,6-Dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy-2(1 H)-pyridinone
• Quantity: 1 mg
• Melting Point: 83°C to 85°C
• Shipping Condition: -20°C
• Molecular Formula: C15H21Cl2NO5
• Color: White
• Purity: 96.1
• Molecular Weight (g/mol): 366.2, 366.24
• InChI Key: OVULNOOPECCZRG-CIUDSAMLSA-N
• SMILES: COC1=C(OC)C(=O)C(C(=O)[C@@H](C)C[C@H](C)[C@@H](Cl)CCl)=C(O)N1
• IUPAC Name: 3-[(2S,4S,5R)-5,6-dichloro-2,4-dimethylhexanoyl]-2-hydroxy-5,6-dimethoxy-1,4-dihydropyridin-4-one
• Chemical Name or Material: Atpenin A5

Safety and Handling

Product Identifier

• 5-Iodo-2'-deoxyuridine

Signal Word

• Danger

Hazard Category

• Serious eye damage/eye irritation Category 2
• Germ cell mutagenicity Category 1A
• Reproductive toxicity Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.
• H340-May cause genetic defects.
• H361-Suspected of damaging fertility or the unborn child.

Precautionary Statement

• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P321-Specific treatment (see on this label).
• P405-Store locked up.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information

• MIXTURE LIST-Contain: 5-Iodo-2'-deoxyuridine