Invitrogen™ ATP6V1G2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5140243

Product Code. 17844760

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: NLSAEVEQAT RRQVQGMQSS QQRNRERVLA QLLGMVC Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 97%.

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of three V1 domain G subunit proteins. This gene had previous gene symbols of ATP6G and ATP6G2. Alternatively spliced transcript variants encoding different isoforms have been described. Read-through transcription also exists between this gene and the downstream DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B (DDX39B) gene.

Specifications

• Antigen: ATP6V1G2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ATP6V1G2
• Gene Alias: 1500002D01Rik; ATP6G; Atp6g2; ATP6V1G1; Atp6v1g2; ATPase H+ transporting V1 subunit G2; ATPase, H+ transporting, lysosomal (vacuolar proton pump); ATPase, H+ transporting, lysosomal 13kD, V1 subunit G; ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2; ATPase, H+ transporting, lysosomal V1 subunit G2; ATPase, H+ transporting, V1 subunit G; H(+)-transporting two-sector ATPase, subunit G2; LOC514368 protein; lysosomal 13kDa; NG38; vacuolar ATP synthase subunit G 2; vacuolar ATPase NG38; vacuolar proton pump G subunit 2; vacuolar proton pump subunit G 1; Vacuolar proton pump subunit G 2; VAG2; V-ATPase 13 kDa subunit 2; V-ATPase subunit G 1; V-ATPase subunit G 2; VMA10; V-type proton ATPase subunit G 1; V-type proton ATPase subunit G 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 534
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O95670
• Gene Symbols: ATP6V1G2
• Immunogen: Recombinant protein corresponding to Human ATP6V1G2. Recombinant protein control fragment (Product #RP-109164).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG