Invitrogen™ ATP6V1F Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA563998

Product Code. 15781762

Description

Immunogen sequence: DIGIILINQY IAEMVRHALD AHQQSIPAVL EIPSKEHPYD AAKDSILRRA RGMFTAEDL Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

ATP6V1F encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is the V1 domain F subunit protein.

Specifications

• Antigen: ATP6V1F
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Atp6v1f
• Gene Alias: 1110004G16Rik; adenosinetriphosphatase 14k chain; ATP6S14; ATP6V1F; ATPase H+ transporting V1 subunit F; ATPase, H transporting, lysosomal V1 subunit F; ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F; ATPase, H+ transporting, lysosomal V1 subunit F; ATPase, H+ transporting, V1 subunit F; ATPase, vacuolar, 14 kD; H(+)-transporting two-sector ATPase, 14kD subunit; vacuolar ATP synthase subunit F; vacuolar proton pump F subunit; vacuolar proton pump subunit F; VATF; V-ATPase 14 kDa subunit; V-ATPase F subunit; V-ATPase subunit F; Vma7; V-type proton ATPase subunit F; v-type proton ATPase subunit F-like
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9296
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q16864
• Gene Symbols: Atp6v1f
• Immunogen: Recombinant protein corresponding to Human V-ATPase F. Recombinant protein control fragment (Product #RP-103427).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG