Invitrogen™ ATP6V1A Recombinant Rabbit Monoclonal Antibody (K01_2L48)

Product Code.	Quantity
30829391	100 μL
30828086	50 μL

Product Code. 30829391 Supplier Invitrogen™ Supplier No. MA564002

Description

Rabbit Recombinant Monoclonal Antibody

ATP6V1A Recombinant Monoclonal Antibody for Western Blot, IHC (P)

ATP6V1A encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues. Transcript variants derived from alternative polyadenylation exist.

Specifications

• Antigen: ATP6V1A
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Recombinant Monoclonal
• Clone: K01_2L48
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: 50mM tris glycine with 0.05% BSA, 40% glycerol, 150mM NaCl and 0.01% sodium azide; pH 7.4
• Gene: ATP6V1A
• Gene Accession No.: P38606, P50516
• Gene Alias: 70-kDa subunit; AI647066; Atp6a1; Atp6a2; Atp6v1a; Atp6v1a1; ATPase H+ transporting V1 subunit A; ATPase, H+ transporting, lysosomal (vacuolar proton pump), alpha 70 kDa, isoform 2; ATPase, H+ transporting, lysosomal 70kD, V1 subunit A, isoform 1; ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A; ATPase, H+ transporting, lysosomal V1 subunit A; ATPase, H+ transporting, lysosomal, subunit A1; ATPase, H+ transporting, V1 subunit A, isoform 1; ATPase, H+ transporting, V1 subunit A1; H(+)-transporting two-sector ATPase, subunit A; H+-transporting ATPase chain A, vacuolar (VA68 type); HO68; lysosomal 70kDa; VA68; vacuolar ATP synthase catalytic subunit A, ubiquitous isoform; vacuolar ATPase isoform VA68; vacuolar proton pump alpha subunit 1; vacuolar proton pump subunit alpha; V-ATPase 69 kDa subunit; V-ATPase 69 kDa subunit 1; V-ATPase A subunit 1; V-ATPase subunit A; Vma1; VPP2; V-type proton ATPase catalytic subunit A
• Gene Symbols: ATP6V1A
• Host Species: Rabbit
• Immunogen: Recombinant protein of human ATP6V1A.
• Purification Method: Protein A/G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11964, 523, 685232
• Target Species: Human, Mouse, Rat
• Content And Storage: Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG