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Description
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified.
Specifications
Specifications
| Antigen | ATP1B1 |
| Applications | Immunofluorescence, Immunocytochemistry, Immunoprecipitation, Flow Cytometry, Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 0.27 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | ATP1B1 |
| Gene Accession No. | P05026, P07340, P14094 |
| Gene Alias | ATP1B, ATP1B1, Beta 1 subunit of Na(+) K(+) ATPase, Na+/K+ ATPase beta 1 subunit |
| Gene Symbols | Atp1b1 |
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