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Invitrogen™ ATP11B Polyclonal Antibody

Product Code. 12849142
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Quantity:
100 μg
Unit Size:
100µg
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12849142 100 μg 100µg
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Product Code. 12849142 Supplier Invitrogen™ Supplier No. PA520996

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Description

Rabbit Polyclonal Antibody

A suggested positive control is K562 cell lysate. PA5-20996 can be used with blocking peptide PEP-1110.

ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATP11B
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ATP11B
Gene Accession No. Q9Y2G3
Gene Alias 1110019I14Rik; ATP11B; ATPase class VI type 11B; ATPase IR; ATPase phospholipid transporting 11B (putative); ATPase, class VI, type 11B; ATPIF; ATPIR; KIAA0956; mKIAA0956; P4-ATPase flippase complex alpha subunit ATP11B; Probable phospholipid-transporting ATPase IF; TIEG; TIEG1; truncated ATPase 11B protein
Gene Symbols ATP11B
Host Species Rabbit
Immunogen A 19 amino acid peptide near the amino terminus of human ATP11B.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23200, 76295
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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