Invitrogen™ ATP11B Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA557578

Product Code. 15765471

Description

Immunogen sequence: MKYQEINGRL VPEGPTPDSS EGNLSYLSSL SHLNNLSHLT TSSSFRTSPE NETELIKEHD LFFKAVSLCH TVQISNVQTD CTGDGPWQSN LAPSQLEY Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 80%.

ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.

Specifications

• Antigen: ATP11B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ATP11B
• Gene Alias: 1110019I14Rik; ATP11B; ATPase class VI type 11B; ATPase IR; ATPase phospholipid transporting 11B (putative); ATPase, class VI, type 11B; ATPIF; ATPIR; KIAA0956; mKIAA0956; P4-ATPase flippase complex alpha subunit ATP11B; Probable phospholipid-transporting ATPase IF; TIEG; TIEG1; truncated ATPase 11B protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23200
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y2G3
• Gene Symbols: ATP11B
• Immunogen: Recombinant protein corresponding to Human ATP11B. Recombinant protein control fragment (Product #RP-96268).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG