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  6. Invitrogen™ ATF3 Recombinant Rabbit Monoclonal Antibody (K01_2L45)

Invitrogen™ ATF3 Recombinant Rabbit Monoclonal Antibody (K01_2L45)
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Product Code. 30825630
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Product Code. 30825630 Supplier Invitrogen™ Supplier No. MA563999

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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ S Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%, Pig - 98%, Cynomolgus monkey - 99%.

ATF3 (Activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. It encodes a protein with a calculated molecular mass of 22 kD. ATF3 represses rather than activates transcription from promoters with ATF binding elements. An alternatively spliced form of ATF3 (ATF3 delta Zip) encodes a truncated form ATF3 protein lacking the leucine zipper protein-dimerization motif and does not bind to DNA. In contrast to ATF3, ATF3 delta Zip stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. Three transcript variants encoding two different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ATF3
Applications Western Blot
Classification Recombinant Monoclonal
Clone K01_2L45
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 40% glycerol, 0.05% BSA, 150mM NaCl and 0.01% sodium azide; pH 7.4
Gene ATF3
Gene Accession No. P18847
Gene Alias activating transcription factor 3; ATF 3; ATF3; cAMP-dependent transcription factor ATF-3; cyclic AMP-dependent transcription factor ATF-3; Liver regeneration factor 1; Lrf1; LRF-1; LRFI; LRG-21; MGC137608 protein; transcription factor LRG-21; zgc:55526
Gene Symbols ATF3
Host Species Rabbit
Immunogen Recombinant protein of human ATF3 (aa 1-181).
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 467
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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