Invitrogen™ ASM Recombinant Rabbit Monoclonal Antibody (5T2N2)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA558119

Product Code. 30284232

Description

Immunogen sequence: PARLHRIVPR LRDVFGWGNL TCPICKGLFT AINLGLKKEP NVARVGSVAI KLCNLLKIAP PAVCQSIVHL FEDDMVEVWR RSVLSPSEAC GLLLGSTCGH WDIFSSWNIS LPTVPKPPPK PPSPPAPGAP VSRILFLTDL HWDHDYLEGT DPDCADPLCC RRGSGLPPAS RPGAGYWGEY SKCDLPLRTL ESLLSGLGPA GPFDMVYWTG DIPAHDVWHQ TRQDQLRALT TVTALVRKFL GPVPVYPAVG NHESTPVNSF PPPFIEGNHS S.

The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Three transcript variants encoding two different isoforms have been found for this gene.

Specifications

• Antigen: ASM
• Classification: Recombinant Monoclonal
• Concentration: 2.03 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: P17405, Q04519
• Gene Symbols: Smpd1
• Immunogen: Recombinant protein (or fragment).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin)
• Clone: 5T2N2
• Conjugate: Unconjugated
• Gene: Smpd1
• Gene Alias: Acid sphingomyelinase; ASM; aSMase; A-SMase; NPD; Smpd1; Sphingomyelin phosphodiesterase; sphingomyelin phosphodiesterase 1; sphingomyelin phosphodiesterase 1, acid lysosomal; Zn-SMase
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 20597, 308909, 6609
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid