ASGR1 Mouse anti-Human, Mouse, Porcine, Clone: 1G5F5, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66692-1-IG-20UL

Product Code. 16808815

Description

The asialoglycooprotein receptor (ASGPR) is a transmembrane glycoprotein (42 kDa) which mediates binding, internalisation and degradation of extracellular glycoproteins that have exposed terminal galactose residues. The receptor is expressed on the surface of the hepatocytes in a polar manner, i.e. it is present on the sinusoidal and lateral palasma membranes but not on the bile canalicular membrane. The mammalian hepatic ASGPR mediate the endocytosis and degradation of serum proteins from which terminal sialic residues have been removed.The rat asialoglycoprotein receptor (ASGPR) consists of three polypeptide subunits: rat hepatic lectin (RHL)-1, RHL-2 and RHL-3. The monoclonal antibody 8D7 recognizes a subunit-specific epitope of RHL-1 of rat ASGPR. The monoclonal antibody 8D7 is cross reactive with human ASGPR.

Specifications

• Antigen: ASGR1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: P07306, P34927
• Gene Symbols: ASGR1
• Immunogen: ASGR1 Fusion Protein Ag2310
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Pig, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: 1G5F5
• Conjugate: Unconjugated
• Gene: ASGR1
• Gene Alias: ASGP R 1, ASGPR, ASGPR 1, ASGR1, asialoglycoprotein receptor 1, CLEC4H1, Hepatic lectin H1, HL 1, Hs.12056
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 100625649, 11889, 432
• Content And Storage: -20°C
• Form: Liquid