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Tocris Bioscience™ Asenapine maleate
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Product Code. 18702544
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18702544

Brand: Tocris Bioscience™ 3737/10

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This item is not returnable. View return policy

Description

Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent

Asenapine maleate is a novel psychopharmacologic agent. Displays antagonist activity at 5-HT, dopamine, noradrenalin and histamine receptor subtypes (pKi values are 8.60, 8.40, 10.15, 9.75, 10.46, 8.84, 9.60, 9.94, 8.85, 8.90, 8.84, 9.38, 8.95, 8.93, 8.9, 9.49, 8.91, 9.00 and 8.21 for 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT5A, 5-HT6, 5-HT7, D1, D2L, D2S, D3, D4, α1A, α2A, α2B, α2C, H1 and H2 receptors respectively). Displays no appreciable affinity for muscarinic receptors. Exhibits potent activity in animal models predictive of antipsychotic efficacy.
TRUSTED_SUSTAINABILITY

Specifications

Quantity 10 mg
Product Type Asenapine maleate
Purity >98%
Molecular Weight (g/mol) 401.84
Inhibitors Asenapine maleate

For Research Use Only

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