Invitrogen™ ASB2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA529476

Product Code. 13483617

Description

Recommended positive controls: HL-60. Predicted reactivity: Mouse (93%), Rat (93%), Bovine (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. This gene is induced by all-trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.

Specifications

• Antigen: ASB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ASB2
• Gene Alias: 1110008E15Rik; ankyrin repeat and SOCS box containing 2; ankyrin repeat and SOCS box protein 2; ankyrin repeat and SOCS box-containing 2; ankyrin repeat and SOCS box-containing protein 2; ankyrin repeat and SOCS box-containing protein 2a; ankyrin repeat-containing SOCS box protein 2; Asb2; ASB-2; asb2 {ECO:0000312; EMBL:AAH85882.1}; MGC40044
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51676, 65256
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8K0L0, Q96Q27
• Gene Symbols: ASB2
• Immunogen: Recombinant protein encompassing a sequence within the center region of human ASB2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG