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Tocris Bioscience™ ASB 14780
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Product Code. 18748016
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Quantity:
5 mg
Unit Size:
5mg
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Product Code. 18748016

Brand: Tocris Bioscience™ 6316/5

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This item is not returnable. View return policy

Description

Potent and selective cytosolic phospholipase A2 alpha (cPLA2α) inhibitor; active in vivo; orally bioavailable

ASB 14780 is a potent and selective cytosolic phospholipase A2 alpha (cPLA2α) inhibitor (IC50 = 20 nM). Selective for cPLA2α over secreted PLA2α (sPLA2α; exhibits no inhibition at 10 μM). Inhibits cPLA2α-dependent inflammatory responses in vitro in guinea pig and human whole-blood assays. Improves diet-induced liver injury and CCl4-induced hepatic fibrosis in vivo. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 3-(3-Phenethyl-1-(4-phenoxyphenyl)-1 H-indol-5-yl)propanoic acid tris salt
CAS 1069046-00-9
Quantity 5 mg
Target Phospholipase Inhibitors
Molecular Formula C31H27NO3.C4H11NO3
Purity 0.98
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