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Invitrogen™ ARTS Polyclonal Antibody

Product Code. 12858022
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Quantity:
100 μg
Unit Size:
100µg
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12858022 100 μg 100µg
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Product Code. 12858022 Supplier Invitrogen™ Supplier No. PA520001

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Description

Rabbit Polyclonal Antibody

In Western blot applications, this antibody detects a band at ~32kDa. A suggested positive control is human lung tissue lysate. PA5-20001 can be used with blocking peptide PEP-0123.

Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARTS
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene SEPTIN4
Gene Accession No. O43236
Gene Alias 4-Sep; apoptosis-related protein in the TGF-beta signaling pathway; ARTS; Bh5; BRADEION; Bradeion beta; brain protein H5; C17orf47; CE5B3; CE5B3 beta; cell division control-related protein 2; cell division control-related protein 2b; cerebral protein 7; EG3-1RVC; EG3RVC; expression gene 3 in rat visual cortex; expression gene 3-1 in rat visual cortex; H5; hCDCREL-2; hucep-7; MART; M-Septin; OTTMUSG00000001265; peanut-like 2; peanut-like 2 homolog; peanut-like protein 2; PNUTL2; SEP4; Sept4; septin 4; septin H5; Septin4; septin-4; septin-M; Uncharacterized protein C17orf47
Gene Symbols SEPTIN4
Host Species Rabbit
Immunogen A synthetic peptide corresponding to amino acids near the amino terminus of human ARTS.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5414
Target Species Human
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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