Invitrogen™ ARSA Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA595910

Product Code. 16548751

Description

Immunogen sequence: LMADAQRQDR PFFLYYASHH THYPQFSGQS FAERSGRGPF GDSLMELDAA VGTLMTAIGD LGLLEETLVI FTADNGPETM RMSRGGCSGL LRCGKGTTYE GGVREPALAF WPGHIAPGVT HELASSLDLL PTLAALAGAP LPNVTLDGFD LSPLLLGTGK SPRQSLFFYP SYPDEVRGVF AVRTGKYKAH FFTQGSAHSD TTADPACHAS SSLTAHEPPL LYDLSKDPGE NYNLLGGVAG ATPEVLQALK QLQLLKAQLD AAVTFGPSQV ARGEDPALQI CCHPGCTPRP ACCHCPDPHA; Positive Samples: Jurkat, HeLa, HepG2, A-549, Mouse testis, Mouse liver, Mouse brain; Cellular Location: Lysosome.

The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy, a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.

Specifications

• Antigen: ARSA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARSA
• Gene Alias: ARSA; ARSA1; ARSA-I; Arylsulfatase A; Arylsulfatase A component B; Arylsulfatase A component C; As2; As-2; ASA; AS-A; ASNA-I; ATPase ASNA1; AW212749; cerebroside-sulfatase; EC 3.1.6.8; GET3; hASNA-I; MLD; TISP73; TRC40
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11883, 410
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.22 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P15289, P50428
• Gene Symbols: ARSA
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 210-509 of human ARSA (NP_0004783).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG