Invitrogen™ ARRDC3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5106544

Product Code. 16612985

Description

Antibody detects endogenous levels of total ARRDC3.

Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors. Plays a role in NEDD4-mediated ubiquitination and endocytosis of activated ADRB2 and subsequent ADRB2 degradation. May recruit NEDD4 to ADRB2. Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes.

Specifications

• Antigen: ARRDC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARRDC3
• Gene Alias: AI450344; alpha-arrestin 3; ARRDC3; arrestin domain containing 3; arrestin domain-containing protein 3; Kiaa1376; Liver regeneration-related protein LRRG00048; LRRGT00048; mKIAA1376; TBP-2-like inducible membrane protein; thioredoxin-binding protein-2-like inducible membrane; TLIMP
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 105171, 309945, 57561
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q6TXF1, Q7TPQ9, Q96B67
• Gene Symbols: ARRDC3
• Immunogen: A synthesized peptide derived from human ARRDC3(Accession Q96B67), corresponding to amino acid residues Q376-R414.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG