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ARHGEF1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Product Code. 16888383 Shop All Proteintech Products
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150 μL
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16888383 20 μL 20µL
16878383 150 μL 150µL
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Product Code. 16888383 Supplier Proteintech Supplier No. 113631AP20UL

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Rabbit Polyclonal Antibody

The Ras superfamily of GTPases, which can be subdivided into the Ras, Rho/Rac, Sar, Rab, ARF and Ran subfamilies, controls multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling and cell growth. The Ras superfamily of GTPases function as regulated switches that toggle between a biologically active GTP-bound and an inactive GDP-bound form. This activation is catalyzed by guanine nucleotide exchange factors (GEFs). The Dbl-related proteins are a large family of structurally related molecules that have a common ability to catalyze GEF activity for specific members of the Ras family. Dbl-related proteins include FGD1, Lsc, RhoGEF p115, Lfc, Lbc and Brx. Lsc, Lbc and Lfc share sequence homology and show exchange activity toward Rho family GTPases. RhoGEF p115 catalyzes GEF activity for Rho but not Rac, Cdc42 or Ras GTPases.

Specifications

Antigen ARHGEF1
Applications Immunocytochemistry, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 0.39 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene ARHGEF1
Gene Accession No. Q61210, Q92888
Gene Alias ARHGEF1, GEF1, LBCL2, LSC, P115 RHOGEF, p115RhoGEF, SUB1.5
Gene Symbols ARHGEF1
Host Species Rabbit
Immunogen ARHGEF1 Fusion Protein Ag1905
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16801, 9138
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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