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Invitrogen™ ARHGDIG Polyclonal Antibody

Product Code. 16322005
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Quantity:
100 μL
Unit Size:
100µL
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16322005 100 μL 100µL
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Product Code. 16322005 Supplier Invitrogen™ Supplier No. PA585053

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DKEGGPPAVD EVLDEAVPEY RAPGRKSLLE IRQLDPDDRS LAKYKRVLLG PLPPAVDPSL PNV Highest antigen sequence indentity to the following orthologs: Mouse - 70%, Rat - 42%.

The Ras superfamily of small GTP-binding proteins are critical mediators of diverse cell signaling pathways, including those leading to proliferation, cytoskeletal organization and secretion. The counter-conversion of the active GTPbound form of these proteins to their inactive GDP-bound form is influenced by two types of regulatory proteins: those that alter the intrinsic GTPase activity of the GTP-binding proteins and those that alter the rate of GDP/GTP exchange. Guanine nucleotide-releasing factors (GRFs) increase the GDP dissociation rate, while GDP-dissociation inhibitors (GDIs) decrease the dissociation rate. The Rho GDI subfamily is composed of Rho GDIalpha, Ly-GDI (also known as Rho GDIbeta and previously known as GDI/D4) and Rho GDIgamma. The Rho GDI proteins interact with and have varying affinities for several Ras-like GTP binding proteins, including Rho A, Rho B, Rac and Cdc42. Ly-GDI is expressed only in hematopoietic cells, predominantly in B and T lymphocyte cell lines.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ARHGDIG
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ARHGDIG
Gene Accession No. Q99819
Gene Alias Arhgdig; Gdi5; guanosine diphosphate (GDP) dissociation inhibitor 5, Rho associated; rho GDI 3; Rho GDIgamma; Rho GDP dissociation inhibitor (GDI) gamma; Rho GDP dissociation inhibitor gamma; rho GDP-dissociation inhibitor 3; RhoGDI gamma; Rho-GDI gamma; Rho-GDI2; Rho-GDI-3; RHOGDI-3; Rho-GDIgamma; RIP2
Gene Symbols ARHGDIG
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ARHGDIG. Recombinant protein control fragment (Product #RP-101622).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 398
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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