Invitrogen™ ARHE Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA563863

Product Code. 15771632

Description

Immunogen sequence: SHVATLACVN KTNKNVKRNK SQRATKRISH MPSRPELSAV ATDLRKDKAK SCTVL Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

Members of the Rho family of Ras-related GTPases, such as ARHE, regulate the organization of the actin cytoskeleton in response to extracellular growth factors. Like Ras, Rho family members appear to cycle between an inactive GDP-bound form and an active GTP-bound form. Three major regulators of Rho activity have been identified: RhoGDIs, which interact with the GDP-bound Rho proteins to keep them in a resting complex; GEFs, which promote GDP/GTP exchange leading to activation of Rho proteins; and GAPs, which stimulate GTP hydrolysis and return the activated Rho protein to its inactive form.

Specifications

• Antigen: ARHE
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RND3
• Gene Alias: 2610017M01Rik; AI661404; Arhe; memB; MemB protein; Protein MemB; ras homolog gene family, member E; Rho family GTPase 3; Rho related protein Rnd3/Rho8; rho8; RHOE; rho-related GTP-binding protein Rho8; Rho-related GTP-binding protein RhoE; Rnd3; small GTP binding protein Rho8
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 390
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P61587
• Gene Symbols: RND3
• Immunogen: Recombinant protein corresponding to Human ARHE. Recombinant protein control fragment (Product #RP-103783).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG