Invitrogen™ ARHE Monoclonal Antibody (5C7E8)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA531896

Product Code. 16355324

Description

MA5-31896 has been tested in indirect ELISA.

Members of the Rho family of Ras-related GTPases, such as ARHE, regulate the organization of the actin cytoskeleton in response to extracellular growth factors. Like Ras, Rho family members appear to cycle between an inactive GDP-bound form and an active GTP-bound form. Three major regulators of Rho activity have been identified: RhoGDIs, which interact with the GDP-bound Rho proteins to keep them in a resting complex; GEFs, which promote GDP/GTP exchange leading to activation of Rho proteins; and GAPs, which stimulate GTP hydrolysis and return the activated Rho protein to its inactive form.

Specifications

• Antigen: ARHE
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: P61587
• Gene Symbols: RND3
• Immunogen: Purified recombinant fragment of human RND3 (AA: 104-241) expressed in E. coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 5C7E8
• Conjugate: Unconjugated
• Gene: RND3
• Gene Alias: 2610017M01Rik; AI661404; Arhe; memB; MemB protein; Protein MemB; ras homolog gene family, member E; Rho family GTPase 3; Rho related protein Rnd3/Rho8; rho8; RHOE; rho-related GTP-binding protein Rho8; Rho-related GTP-binding protein RhoE; Rnd3; small GTP binding protein Rho8
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 390
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid