Invitrogen™ ARFGAP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA578819

Product Code. 15914405

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human MOLT-4 whole cell, human Caco-2 whole cell, human HepG2 whole cell, rat brain tissue, mouse brain tissue. IHC: mouse brain tissue, rat brain tissue. ICC/IF: CACO-2 cell. Flow: HepG2 cell.

ArfGAP1 is a 406 amino acid containing regulatory protein with an Arf-GAP domain known to be involved in the activation of the GTPase activity of ADP ribosylation factor (ARF). ArfGAP1, a GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1), promotes the hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles thus playing an important role in membrane trafficking and/or vesicle transport. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been reported. Ubiquitous expression of ArfGAP1 is seen in most tissues.

Specifications

• Antigen: ARFGAP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ARFGAP1
• Gene Alias: ADP ribosylation factor GTPase activating protein 1; ADP-ribosylation factor 1 GTPase activating protein; ADP-ribosylation factor 1 GTPase-activating protein; ADP-ribosylation factor GTPase activating protein 1; ADP-ribosylation factor GTPase-activating protein 1; AI115377; ARF GAP 1; Arf GAP1; ARF1 GAP; ARF1-directed GTPase-activating protein; Arf1gap; ARFGAP1; EGK_02194; GAP protein; HRIHFB2281; RP11-261N11.1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 228998, 246310, 55738
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene Accession No.: Q62848, Q8N6T3, Q9EPJ9
• Gene Symbols: ARFGAP1
• Immunogen: E. coli-derived human ARFGAP1 recombinant protein (Position: M1-Y183).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG