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Invitrogen™ Aquaporin 4 Monoclonal Antibody (CL0178)
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Product Code. 15729240 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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15729240 100 μL 100µL
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Product Code. 15729240 Supplier Invitrogen™ Supplier No. MA524587

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Description

Mouse Monoclonal Antibody

Immunogen sequence: CPDVEFKRRF KEAFSKAAQQ TKGSYMEVED NRSQVETDDL ILKPGVVHVI DVDRGEEKKG KDQSGEVLSS V Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 92%. Binds to an epitope located within the peptide sequence FKRRFKEAFS as determined by overlapping synthetic peptides.

In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Aquaporin 4
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone CL0178
Concentration 1.00 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene AQP4
Gene Accession No. P55087
Gene Alias Aqp4; AQP-4; aquaporin 4; aquaporin type4; Aquaporin4; aquaporin-4; HMIWC2; Mercurial-insensitive water channel; MGC22454; MIWC; MIWC2; WCH4
Gene Symbols AQP4
Host Species Mouse
Immunogen Recombinant protein fragment of Human AQP4 (Product #RP-91109)
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 361
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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