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Invitrogen™ APRIL Polyclonal Antibody

Product Code. 12808192
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12808192 100 μg 100µg
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Product Code. 12808192 Supplier Invitrogen™ Supplier No. PA519976

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Description

Rabbit Polyclonal Antibody

In Western blot applications, this antibody detects a band at ~27kDa. A suggested positive control is Jurkat cell lysate. PA5-19976 can be used with blocking peptide PEP-0101.

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.
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Specifications

Antigen APRIL
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene TNFSF13
Gene Accession No. O75888, Q9D777
Gene Alias 2310026N09Rik; A proliferation-inducing ligand; APRIL; CD256; TALL2; TALL-2; TNF- and APOL-related leukocyte expressed ligand 2; TNF-related death ligand 1; Tnfsf13; TNLG7B; Trdl1; TRDL-1; tumor necrosis factor (ligand) superfamily, member 13; tumor necrosis factor ligand 7B; tumor necrosis factor ligand superfamily member 13; tumor necrosis factor superfamily member 13; tumor necrosis factor-like protein ZTNF2; tumor necrosis factor-related death ligand-1; UNQ383/PRO715; ZTNF2
Gene Symbols TNFSF13
Host Species Rabbit
Immunogen A synthetic peptide corresponding to amino acids within a extracellular domain of human APRIL.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 287437, 69583, 8741
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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