APPL1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA530501

Product Code. 13454997

Description

Recommended positive controls: U87-MG, MCF-7. Predicted reactivity: Mouse (99%), Zebrafish (86%), Xenopus laevis (89%), Pig (98%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signaling and insulin signaling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.

Specifications

• Antigen: APPL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: APPL1
• Gene Alias: 2900057D21Rik; 7330406P05Rik; Adapter protein containing PH domain, PTB domain and leucine zipper motif 1; adaptor protein APPL like; adaptor protein containing pH domain, PTB domain and leucine zipper motif 1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; AI585782; AKT2 interactor; APPL; Appl1; AW209077; BB022931; C88264; DCC-interacting protein 13-alpha; DIP13; DIP13 alpha; DIP13A; DIP13alpha; dip13-alpha; Kiaa1428; MODY14; RGD1309388; signaling adaptor protein DIP13alpha
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26060, 72993
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8K3H0, Q9UKG1
• Gene Symbols: APPL1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 205 of Human APPL1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG