Invitrogen™ Apolipoprotein C1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
17909862	Invitrogen™ PA5145261	200 μL
17909472	Invitrogen™ PA5145262	20 μL

Description

Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins. The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver where it is activated when monocytes differentiate into macrophages. The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues. The human apoC-III gene maps to chromosome 11q23 and encodes a protein that may delay catabolism of triglyceride-rich particles by inhibiting lipoprotein lipase and hepatic lipase. The human apoC-IV gene maps to chromosome 19q13.2 and encodes a 127 amino acid protein that is primarily expressed in the liver.

Specifications

• Antigen: Apolipoprotein C1
• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: P02654, P34928
• Gene ID (Entrez): 11812, 341
• Immunogen: Recombinant Human APOC1 protein, Ser31-Ser83 (Accession #P02654).
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

• Concentration: 0.5 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene Alias: ALPCI; Apoc1; Apo-CI; ApoC-I; Apo-CIB; ApoC-IB; apolipoprotein C1; Apolipoprotein C-I; apolipoprotein C-I variant I; apolipoprotein C-I variant II; Liver regeneration-related protein LRRG04; LRRG04; Truncated apolipoprotein C-I
• Gene Symbols: APOC1
• Isotype: IgG
• Purification Method: Antigen affinity chromatography, Protein A
• Gene: APOC1