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Apilimod, MedChemExpress

Product Code. 16466118
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Product Code. 16466118

Brand: Medchem Express HY14644

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Description

MedChemExpress Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively. Apilimod is a potent and highly selective PIKfyve inhibitor.

Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively. Apilimod is a potent and highly selective PIKfyve inhibitor.

Specifications

Chemical Name or Material Apilimod
Physical Form Solid
CAS 541550-19-0
Color White
Quantity 10 mg
Purity Grade Notes Research
Molecular Formula C23H26N6O2
For Use With (Application) COVID-19-immunoregulation
Synonym STA 5326
Solubility Information DMSO : 100 mg/mL (238.95 mM; Need ultrasonic)
SMILES CC1=CC=CC(/C=N/NC2=CC(N3CCOCC3)=NC(OCCC4=CC=CC=N4)=N2)=C1
Molecular Weight (g/mol) 418.49
Formula Weight 418.49
Percent Purity 98.3%
Grade Research
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Research purposes only

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