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Invitrogen™ APEX2 Polyclonal Antibody
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Product Code. 15944375
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Quantity:
100 μg
Unit Size:
100µg
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15944375 100 μg 100µg
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Product Code. 15944375 Supplier Invitrogen™ Supplier No. PA578791

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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: rat brain tissue, mouse brain tissue, HEK293 whole cell, COS-7 whole cell. Flow: A549 cell.

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair (BER).
TRUSTED_SUSTAINABILITY

Specifications

Antigen APEX2
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene APEX2
Gene Accession No. Q68G58, Q9UBZ4
Gene Alias AP endonuclease 2; AP endonuclease XTH2; Ape2; APEX nuclease (apurinic/apyrimidinic endonuclease) 2; APEX nuclease 2; APEX nuclease-like 2; APEX2; APEXL2; apurinic/apyrimidinic endodeoxyribonuclease 2; apurinic/apyrimidinic endonuclease 2; apurinic/apyrimidinic endonuclease-like 2; Apurinic-apyrimidinic endonuclease 2; C430040P13Rik; DNA-(apurinic or apyrimidinic site) lyase 2; RP5-884M20.3; XTH2; ZGRF2; zinc finger, GRF-type containing 2
Gene Symbols APEX2
Host Species Rabbit
Immunogen E.coli-derived human APEX2 recombinant protein (Position: L102-A210).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27301, 317628, 77622
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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