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Invitrogen™ APC5 Polyclonal Antibody
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Product Code. 16330435
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Quantity:
100 μL
Unit Size:
100µL
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16330435 100 μL 100µL
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Product Code. 16330435 Supplier Invitrogen™ Supplier No. PA583478

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ADGAILDKGR AMFLVAKCQV ASAASYDQPK KAEALEAAIE NLNEAKNYFA KVDCKERIRD VVYFQARLYH TLGKTQERNR CAMLFRQLHQ ELPS Highest antigen sequence indentity to the following orthologs: Mouse - 86%, Rat - 89%.

This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome, a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein, compared to isoform a.
TRUSTED_SUSTAINABILITY

Specifications

Antigen APC5
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Anapc5
Gene Accession No. Q9UJX4
Gene Alias 2510006G12Rik; AA408751; AA536819; AA986414; ANAPC5; anaphase promoting complex subunit 5; anaphase-promoting complex subunit 5; Anpc5; APC5; cyclosome subunit 5; MNCb-2778
Gene Symbols Anapc5
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ANAPC5. Recombinant protein control fragment (Product #RP-104708).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51433
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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