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Invitrogen™ APC4 Polyclonal Antibody

Product Code. 12849092
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Quantity:
100 μg
Unit Size:
100µg
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12849092 100 μg 100µg
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Product Code. 12849092 Supplier Invitrogen™ Supplier No. PA520945

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Description

Rabbit Polyclonal Antibody

A suggested positive control is mouse liver tissue lysate. PA5-20945 can be used with blocking peptide PEP-1059.

A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen APC4
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ANAPC4
Gene Accession No. Q91W96, Q9UJX5
Gene Alias 2610306D21Rik; ANAPC4; anaphase promoting complex subunit 4; anaphase-promoting complex subunit 4; APC4; cyclosome subunit 4; D5Ertd249e
Gene Symbols ANAPC4
Host Species Rabbit
Immunogen A 14 amino acid peptide near the amino terminus of human APC4.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29945, 305420, 52206
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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