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Invitrogen™ APC13 Polyclonal Antibody

Product Code. 12859102
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Quantity:
100 μg
Unit Size:
100µg
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12859102 100 μg 100µg
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Product Code. 12859102 Supplier Invitrogen™ Supplier No. PA520956

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Description

Rabbit Polyclonal Antibody

A suggested positive control is Jurkat cell lysate. PA5-20956 can be used with blocking peptide PEP-1070.

Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC13 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC13 promotes the stable association of APC3/Cdc27 and APC6/Cdc16 with the APC/C.
TRUSTED_SUSTAINABILITY

Specifications

Antigen APC13
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ANAPC13
Gene Accession No. Q8R034, Q9BS18
Gene Alias 1810004D07Rik; ANAPC13; anaphase promoting complex subunit 13; anaphase-promoting complex subunit 13; APC13; cyclosome subunit 13; cylosome subunit 13; SWM1
Gene Symbols ANAPC13
Host Species Rabbit
Immunogen A 17 amino acid peptide near the center of human APC13.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25847, 685029, 69010
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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