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Invitrogen™ APBA2 Polyclonal Antibody

Product Code. 12819202
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Quantity:
100 μg
Unit Size:
100µg
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12819202 100 μg 100µg
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Product Code. 12819202 Supplier Invitrogen™ Supplier No. PA521053

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human brain tissue lysate. PA5-21053 can be used with blocking peptide PEP-1167.

APBA2, a member of the X11 protein family, is a phosphotyrosine-binding domain protein and is a neuronal adapter protein that interacts with amyloid precursor protein (APP) and neuritic plaques in the brains of patients with Alzheimer's disease. It stabilizes APP and inhibits production of proteolytic APP fragments including the Abeta peptide that is deposited in the brains of Alzheimer's disease patients. APBA2 is believed to be involved in signal transduction processes and is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Recent reports suggest that it may also be a candidate gene for autism.
TRUSTED_SUSTAINABILITY

Specifications

Antigen APBA2
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene APBA2
Gene Accession No. Q99767
Gene Alias Adapter protein X11beta; amyloid beta (A4) precursor protein-binding family A member 2 (X11-like); amyloid beta (A4) precursor protein-binding, family A, member 2; amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like); amyloid beta A4 precursor protein-binding family A member 2; amyloid beta precursor protein binding family A member 2; Amyloid-beta A4 precursor protein-binding family A member 2; Apba2; D15S1518E; HsT16821; LIN-10; MGC:14091; Mint 2; Mint2; mint-2; mXllL; Neuronal Munc18-1-interacting protein 2; neuron-specific X11L protein; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein; X11-BETA; X11L; X11-like; X11-like protein; XllL
Gene Symbols APBA2
Host Species Rabbit
Immunogen An 18 amino acid peptide near the center of human APBA2.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 321
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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