Invitrogen™ UGT1A7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA543352

Product Code. 15516012

Description

Peptide sequence: VKTYSTSYTL EDQDREFMVF ADARWTAPLR SAFSLLTSSS NGIFDLFFSN Sequence homology: Human: 100%.

UGT1A7 is an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has moderate glucuronidase activity with phenols.

Specifications

• Antigen: UGT1A7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UGT1A7
• Gene Alias: GNT1; UDP glucuronosyltransferase 1 family, polypeptide A7; UDP glucuronosyltransferase family 1 member A7; UDP glycosyltransferase 1 family, polypeptide A7; UDP-glucuronosyltransferase 1 family polypeptide A7s; UDP-glucuronosyltransferase 1-7; UDP-glucuronosyltransferase 1A7; UDP-glucuronosyltransferase 1-G; UDPGT; UDPGT 1-7; UGT1; UGT1.7; UGT1-07; UGT1A7; UGT1G; UGT-1G
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54577
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9HAW7
• Gene Symbols: UGT1A7
• Immunogen: Synthetic peptide directed towards the N-terminal of human UGT1A7 (aa 74-123).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG