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β-Tubulin, Class III Mouse, Alexa Fluor 488, Clone: TUJ1, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 560338

Product Code. 15810119

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Description

Description

Microtubules are formed by the self assembly of tubulin and are one of the major components of the eukaryotic cytoskeleton. The two main tubulin isoforms, α - and β-tubulin, are usually products of separate genes. The β-tubulin family includes six expressed genes that produce the polypeptide isoforms known as Classes I through VI, each of which have a distinct pattern of expression. Class III β-tubulin is found in neurons and mammalian testis cells and is widely used as a neuronal marker in developmental neurobiology, neoplasia, and stem cell research. Class III β-tubulin expression in neuronal and neuroblastic tumors is differentiation dependent, and its expression in certain non-neuronal neoplasms has been associated with poor prognosis and/or resistance to chemotherapy.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

β-Tubulin, Class III
Monoclonal
Alexa Fluor 488
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Rat brain microtubules
100 Tests
Cell Biology
Human, Rat
IgG2a
In vitro Assay
TUJ1
tubulin, beta 3; MC1R; TUBB3; TUBB4; tubulin, beta-4
Mouse
Affinity Purified
RUO
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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