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TROP-2 Mouse anti-Human, Unlabeled, Clone: 162-46, BD
Mouse Monoclonal Antibody
Brand: BD Biosciences 551317
Description
Trop-2/GA733-1 is a cell surface glycoprotein that was originally identified on human trophoblast and choriocarcinoma cell lines and has been shown to be expressed in most human carcinomas. Trop-2 has been cloned and shown to encode a type-1 transmembrane protein with a single transmembrane domain. Furthermore, research has shown Trop-2 to be involved in the transduction of an intracellular calcium signal, although the exact physiological mechanism has yet to be elucidated. The antibody recognizes human Trop-2. Cells from the human choriocarcinoma cell line BeWo were used as the immunogen.
Host Species: Mouse
Clone: 162-46
Isotype: IgG1 κ
Species Reactivity: Human
Immunogen: Human choriocarcinoma cell line BeWo
Flow Cytometry
Specifications
| TROP-2 | |
| Monoclonal | |
| 0.5mg/mL | |
| GA733-1; TROP2; EGP-1; EGP1; GP50; M1S1; TACD2 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C |
| Flow Cytometry | |
| 162-46 | |
| Unconjugated | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Human choriocarcinoma cell line BeWo | |
| 100 μg | |
| Cell Biology | |
| Human | |
| IgG1 κ |
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